Anyone have experience with Nucynta ER (tapentadol) for TN II neuropathic pain?

I have been on Oxycontin ER lately and am not getting adequate pain relief with 10 mg twice/day..only constipation...lol. I am also starting to slide down the depression slope again and do not want another go-round with antidepressants that gave me horrid side effects. I would like to wean off the oxy and try tramadol because of its serotonin-NE reuptake inhibition. I talked to my MD and she thought it a good idea. However....recently have read info about bad reactions & poor pain relief with tramadol and better pain relief and less side effects with Nucynta. Suggestions??

So sorry you also are having a bad couple of weeks. It really sucks. I have tried both amytriptilene and nortriptilene and neither one helped my pain and both turned me into a hung-over feeling zombie. Trileptal, trazadone, dilantin, gabapentin, lamotrigine, keppra all did nothing but f-up my brain and turn me into a crazy person with NO patience for anything whatsoever. Ruined many relationships and caused me to sell my wonderful house....of course now, I have absolutely no recolletion of doing any of these things. I guess I am lucky in that my Dr. is very agreeable to my needs. I bring her a lot of research about TN too. When she feels unsure about handling a drug conversion, she sends me to pain management for them to do the titrating (and they are idiots and ignorant about TN, so I have to bite my tongue a lot). Still think I am going to try the Nucynta....if it doesn't work I can always go back to the oxy and increase the dose.

Damaged by Sargenti Paste R/C said:

I took hydro 3x day and when I moved out of town I couldn't find a doctor who would help. I finally went to a GP and didn't tell him the problems until I was already a patient. He didn't want to give me hydro for continuous use so he gave me nucynta and it did nothing. He finally agreed to give me hydro 2x day but wants me to find another doctor to help. I keep getting turned down by neuros and pain clinics. I guess they don't want patients that they can't fix. I've been on trileptal and it also did nothing. I'm headed down that slippery slope too... Haven't gotten out of bed for 2days and pissed at a good friend who knows what I should do even tho she has no clue what I lie with. Serious contributor to my slippery slope. Have you tried elavil/amytriptiline? It helps me and has some antidepressant properties but obviously not the answer since I take it and am where I am.

I have constant burning pain. 6-8/10 on any given day. Recently a 9 which I think is because I can only get hydro 2x day now. I get tired of people saying I'm probably addicted to the hydro. I HAVE TO TAKE hydro because I'm really addicted to freaking pain. If I could get rid of it, the hydro would go away immediately. I don't have problems with withdrawals from changing meds, including abruptly stopping antidepressants...did it for years before this happened. I hate this shit and made worse by 3 dentists whose lives go on like mine should be. Sorry to rant. Not a good day / 2 weeks.