Something New in Face Pain Treatment Research

The following new medication is in the Phase 2b Trials stage, as an improved treatment for Migraine. However, it also appears to me that it may have potential for treating all types of trigeminal pain.

http://www.colucid.com/lasmiditan

I corresponded with the staff at Colucid's website, with the following result:

Comment/Question 

I would appreciate hearing from anyone on your scientific staff concerning the possible application of Lasmiditan in treatment of trigeminal neuralgia or trigeminal neuropathic pain. Does targeting of this drug against a specific gene in the trigeminal distribution offer promise of suppressing pain processes other than migraine? I look forward to your reply.
Richard A. Lawhern, Ph.D.
Site Administrator and Moderator Living With TN
http://www.livingwithtn.org

Site Staff Response:

Dear Richard, 

Thank you for your thoughtful question. We believe that lasmiditan may have potential for trigeminally-mediated pain other than migraine, but as yet there are no data. Such studies could be conducted following its approval for use in migraine.

Sincerely,
Kathy Kelly
for Dr. Nadia Rupniak, VP of R&D

I am also checking out the potentials of this targeted approach to trigeminal nerve pain, with members of the Medical Advisory Board of the TN Association.

Is it just me, or is anyone else having trouble viewing this?

All I can see is half of the first sentences.....

not just you Tina P, that's all I can see too

Wups... Let's try the included text one more time:

My inquiry:

I would appreciate hearing from anyone on 
your scientific staff concerning the possible
application of Lasmiditan in treatment of
trigeminal neuralgia or trigeminal neuropathic pain.
Does targeting of this drug against a specific gene in the
trigeminal distribution offer promise of suppressing
pain processes other than migraine?

look forward to your reply.

===============
Staff Response:

Dear Richard, Thank you for your thoughtful question. 
We believe that lasmiditan may have potential for
trigeminally-mediated pain other than migraine,
but as yet there are no data. Such studies
could be conducted following its approval for
use in migraine.

Sincerely,
Kathy Kelly for Dr. Nadia Rupniak, VP of R&D

I can read the full view in my phone but not on my computer screen.

Red, Can you copy the text and paste it into a new discussion?

Ya the right side is cut off.

Is everybody seeing the revised text now?

R

Where is the new info on who has TN?

Open the "Who Has TN" sub-tab under our "Face Pain Info" icon on the site menu above...

Regards, Red

Larry said:

Where is the new info on who has TN?

Well....this is encouraging indeed. Wowzaaaa!!!

Thanks Red for your efforts to find possibility of new medicine to solve this monstrous disease. I am 67 now and m 50 years into this disease losing all my youth in agony of pain. We need someone like you to keep a watch on the research and keep us informed.
Particularly the young ones. God bless you.
Yakub

A new medication! Thank God! Let's hope it's out soon. Could be what many of us are waiting for! Thanks Richard!

Red, this is great news except that it is still in clinical phases, which means we are at the very least 10 years out from it being mass marketed. I have been involved with clinical studies before through Northwestern University and any clinical study drug has between 10 and 15 year wait, it just depends on if there will be a second double blind study doe before it is released. So, is there anyway to find out where any of the studies are being done so that we can apply to see if any of us are eligible to participate? I am only 6 months into ATN but have been through the gammet of drugs and therapies and I have no relief at all, I cannot imagine waiting another year much less ten or more for some study drug. Thanks for the info.

There is a trials database at the US National Institutes of Health. You can look up the status of studies by keyword at http://www.clinicaltrials.gov/

Regards, Red

many thanks red

I have been experiencing teribble headaches, all three at the same time sometimes. Mostly migraine and cluster with my scalp pain from TN. I have now been on the search for migraine drugs. I am using imitrex with success but it is the nose spray and has a nasal drip that can induce vomitting if I am not already at it. I am so excited when I hear of new stuff, even though I know my doctor does not like anything new. I sure wish I new how to get involved with these clinical trials. I would gladly be a guinea pig.

Tree69

In most cases, when a clinical trial is begun, entry will be closed to new applicants. It's a necessary part of managing the expense of trials. However, I will try to monitor for outcomes and report to the forums here at Living With TN

Regards, Red