The following new medication is in the Phase 2b Trials stage, as an improved treatment for Migraine. However, it also appears to me that it may have potential for treating all types of trigeminal pain.
I corresponded with the staff at Colucid's website, with the following result:
Comment/Question
I would appreciate hearing from anyone on your scientific staff concerning the possible application of Lasmiditan in treatment of trigeminal neuralgia or trigeminal neuropathic pain. Does targeting of this drug against a specific gene in the trigeminal distribution offer promise of suppressing pain processes other than migraine? I look forward to your reply. Richard A. Lawhern, Ph.D. Site Administrator and Moderator Living With TN http://www.livingwithtn.org
Site Staff Response:
Dear Richard,
Thank you for your thoughtful question. We believe that lasmiditan may have potential for trigeminally-mediated pain other than migraine, but as yet there are no data. Such studies could be conducted following its approval for use in migraine.
Sincerely, Kathy Kelly for Dr. Nadia Rupniak, VP of R&D
I am also checking out the potentials of this targeted approach to trigeminal nerve pain, with members of the Medical Advisory Board of the TN Association.
Wups... Let's try the included text one more time:
My inquiry:
I would appreciate hearing from anyone on your scientific staff concerning the possible application of Lasmiditan in treatment of trigeminal neuralgia or trigeminal neuropathic pain. Does targeting of this drug against a specific gene in the trigeminal distribution offer promise of suppressing pain processes other than migraine?
look forward to your reply.
=============== Staff Response:
Dear Richard, Thank you for your thoughtful question. We believe that lasmiditan may have potential for trigeminally-mediated pain other than migraine, but as yet there are no data. Such studies could be conducted following its approval for use in migraine.
Sincerely, Kathy Kelly for Dr. Nadia Rupniak, VP of R&D
Thanks Red for your efforts to find possibility of new medicine to solve this monstrous disease. I am 67 now and m 50 years into this disease losing all my youth in agony of pain. We need someone like you to keep a watch on the research and keep us informed.
Particularly the young ones. God bless you.
Yakub
Red, this is great news except that it is still in clinical phases, which means we are at the very least 10 years out from it being mass marketed. I have been involved with clinical studies before through Northwestern University and any clinical study drug has between 10 and 15 year wait, it just depends on if there will be a second double blind study doe before it is released. So, is there anyway to find out where any of the studies are being done so that we can apply to see if any of us are eligible to participate? I am only 6 months into ATN but have been through the gammet of drugs and therapies and I have no relief at all, I cannot imagine waiting another year much less ten or more for some study drug. Thanks for the info.
I have been experiencing teribble headaches, all three at the same time sometimes. Mostly migraine and cluster with my scalp pain from TN. I have now been on the search for migraine drugs. I am using imitrex with success but it is the nose spray and has a nasal drip that can induce vomitting if I am not already at it. I am so excited when I hear of new stuff, even though I know my doctor does not like anything new. I sure wish I new how to get involved with these clinical trials. I would gladly be a guinea pig.
In most cases, when a clinical trial is begun, entry will be closed to new applicants. It's a necessary part of managing the expense of trials. However, I will try to monitor for outcomes and report to the forums here at Living With TN