Medication side effects and weird (wonderful?) outcome or just a fluke?

First, let me give a little background. I was diagnoised with TN by an oral surgeon this past November 2011. He referred me to a neurologist who confirmed the diagnosis.

My first episode of what I now understand is Type 1 TN pain occurred following a bad experience at the dentist's office. I was having impressions made for two upper teeth crowns. The technician allowed the impression "goop" to harden too long and could not remove the impression tray from my mouth. She tugged, pulled, wiggled and did everything short of putting her foot on my chest and yanking the thing out of my mouth. Finally, she gave up and called the dentist who did manage to remove the impression tray.

The next day out of the blue I felt a flash of pain in my lower jaw that almost dropped me to my knees. It was like an electrified ice pick had been jabbed into my jaw. As I said...it was over in a flash but I'd never experienced any pain like it before and it left me weak. My first thought was that I had an exposed nerve in a lower tooth and I guarded that side of my mouth the rest of the day. The next few days it happened several times again but not quite as intense. As I had a return visit scheduled for the crowns in a couple of days, I postponed calling the dentist.

I discussed the pain with the dentist first thing on my return visit. She seemed perplexed...looked at my x-rays...assured me there were no dental problems to account for the pain and just sort of dismissed it. Two days after that visit, the pains returned with renewed intensity and I called the dentist and insisted on an appointment that day. She physically examined all my back teeth and tried to stimulate the pain but nothing happened. She took new x-rays...nothing abnormal to indicate pain. She referred me to the oral surgeon and that's when I received the diagnosis as "classic symptoms of TN".

I was already taking 300 mg of gabapentin daily as part of my fibromyalgia regimen and the oral surgeon increased it to 900 mg daily. The pain continued and he referred me to the neurologist. The neurologist upped the dosage to 1200 mg and added 20 mg of baclofen....then to 1600 mg of the gabapentin and 30 mg of baclofen.

From the beginning of this, I experienced very unpleasant side effects.... nausea, dizziness, blurred vision, etc. Each time my dosage was increased the side effects were worse and I was unable to function at times. On Sunday, March 18th , all hell broke loose. I awoke with a horrible, all-over sick feeling and barely made it to the bathroom when the projectile vomiting began. I felt a little better after that but waited an hour before taking my morning meds and eating a small breakfast. Then the vomiting started again. Even a few sips of water triggered the vomiting...all day I experienced extreme weakness, dizziness and what I can only describe as feeling like my whole body was buzzing. I also felt electric- like shocks in my fingertips and toes. I finally called my daughter and she insisted on taking me to the ER.

The ER doctor ordered blood work and a CT scan because my speech was slurred and I was almost hostile insisting that it was my TN medication. He determined that I wasn't having a stroke but I was dehydrated had a bladder infection. He reviewed all the medications I was taking for the TN, fibromyalgia, blood pressure and degenerative joint disease. As it turned out, four of my six medications all had the same side effects...and...in his opinion, the side effects were being compounded as a result. In fact, one anti-convulsant med for restless leg syndrome that I had taken for years was totally unnecessary as gabapentin is also prescribed as a treatment for RLS.

The ER doctor recommended that I consult my primary physician and neurologist for eliminating all my medications other than the gabapentin and my blood pressure medicine. My daughter called my GP and neurologist that night and left a voicemail message relating the ER doctors's recommendation. The GP responded the next morning giving his OK re the four meds he had prescribed...staying on the lisinopril, of course. I still haven't heard from the neurologist re the baclofen and my next appointment with her isn't until the middle of June.

Whether I've been wise or foolish I don't know...but I stopped the baclofen and am taking only the 1600 mg of gabapentin for the TN and lisinopril for my blood pressure. It's been over two weeks since that horrible episode. My bladder infection has cleared and I've been functional with minimal TN pain. I still have significant problems with eating, brushing my teeth and a couple other salivary gland triggers but I've learned to cope and deal with those.

I've lived with the fibromyalgia and joint pain for years to the point it's almost normal for me. To avoid compounding the side effects with meloxicam, etc., I'm taking 800 mg of OTC ibuprofen only as needed when I'm especially uncomfortable.

I hope my respite from the horrendous side effects is not just a fluke and that I won't regret dropping the baclofen for TN. I'm wondering if I should try adding the baclofen again at the original 20 mg daily dosage.

When I took baclofen, it gave me a horrible headache in the lower back of my head. So I vote no, on trying to take it again at a lower dosage. LOL But seriously, what an ordeal for you!! Yikes! I hope things continue to go well for you Mary.

Thanks Min C. Since I've felt so much better the last few days, my instinct was to leave it off too. I also had a dull, heavy feeling in the back of my head but not actually pain. I didn't connect it to the baclofen though.

LOL....since I posted this, I've discovered another problem. I haven't been able to brush my teeth or use mouth wash as I normally would since this whole thing began. Just a few minutes ago I noticed a horrible taste in my mouth and looked at my tongue....IT WAS BLACK!! I mean really black. I wet my toothbrush and brushed the side of my tongue that doesn't trigger the pain. My toothbrush turned as dirty as if I had used it on a dirty floor. I Googled "black tongue" and, sure nuff, there's a condition called "Hairy Black Tongue" and it's caused by poor oral hygiene. LOL....good grief!! At least it's not supposed to be serious and the recommended treatment is improved oral hygiene.

Dear Mary -

read all your story. be strong. good it's more under control now.

and it's seems you have a great Daughter ! not giving up and insisiting to get you the help you need !!!

it's very very important

Oh Mary, how dreadful for you, it did not suit me either but not to the extreme you have endured. :(

Oh my... Wow I hope it goes away soon!!! Keep us posted. Min

Thank you Nir......and, yes, I'm blessed to have a wonderful daughter who looks out for me. I've been reading your discussions too and I appreciate the time you've taken to encourage and support me. I've been shocked to learn so many people suffer from this kind of pain; yet, each and every one here forgets their own pain long enough to reach out to others. What a remarkable group of people!!

Mary

Nir Morita said:

Dear Mary -

read all your story. be strong. good it's more under control now.

and it's seems you have a great Daughter ! not giving up and insisiting to get you the help you need !!!

it's very very important

Hi Mary, I read your story. I am so sorry you went through all this. It sounds like things have gotten under control now. Your dental problems sound like mine were too. I kept insisting they do something, which they did but only added to the problem as it got worse. I too was astounded by the electric shocks which I had about 3 times. I did not know pain could be so bad but luckily they did not last long, but long enough to about scare me to death!

I am now taking Baclofen 40 mg. total and will probably go up to 60mg slowly. For a while 20 mg was working and then I foolishly cut back because I was doing fairly well. Then it hit me hard so I am now trying to get back to at least feeling better.

I have pain when I eat so I blend everything with a hand blender I have to make it almost liquid. I still have some pain when eating-drinking it. Also, I have sharp pains when I talk which is maddening, but I talk anyway. lol It helps if I talk calmly. Everything is better if I am relaxed.

Anyway, I have just joined this site and have just been diagnosed two months ago so it is all very new to me.

Hi Mary Helen....thanks for commenting. When I was having such a problem with the side effects of my meds, I couldn't talk either without some pretty rough pain. Who knows why but that problem has lessened quite a bit too. I'll tell you what, just when I think I've figured out where I stand, things change again. Thank goodness, I've had about two weeks of relative ease but I live in fear those horrible pains will strike again.

You mentioned you had also had dental problems prior to your TN pain. I'm curious as to what happened to you. I asked my neurologist if my bad dental experience could have caused my TN and she said "No!" Personally, I think she's wrong as I've read about several people here who experienced their first episode of TN pain following some kind of dental procedure. Woe be unto my dentist if I ever find out for sure that this hell was visited on me as a result of my bad experience in her office. LOL...she just might be giving my great grandchildren free dental service 20 years from now. I'm just joking but it does seem to me that dentists should be better educated about TN and how to avoid putting their patients in jeopardy. There just seems to be too many coincidences re dental problems precipitating TN pain in the short time I've belonged to this site for there not to be some correlation.

I left a Wall Comment on your page earlier and I look forward to hearing more of your story when you have an opportunity.

~Mary

MaryHelenL said:

Hi Mary, I read your story. I am so sorry you went through all this. It sounds like things have gotten under control now. Your dental problems sound like mine were too. I kept insisting they do something, which they did but only added to the problem as it got worse. I too was astounded by the electric shocks which I had about 3 times. I did not know pain could be so bad but luckily they did not last long, but long enough to about scare me to death!

I am now taking Baclofen 40 mg. total and will probably go up to 60mg slowly. For a while 20 mg was working and then I foolishly cut back because I was doing fairly well. Then it hit me hard so I am now trying to get back to at least feeling better.

I have pain when I eat so I blend everything with a hand blender I have to make it almost liquid. I still have some pain when eating-drinking it. Also, I have sharp pains when I talk which is maddening, but I talk anyway. lol It helps if I talk calmly. Everything is better if I am relaxed.

Anyway, I have just joined this site and have just been diagnosed two months ago so it is all very new to me.

Hi Mary, Thank you for the Wall message and for answering me. No one else but people on this site know the strange things we are dealing with. The Baclofen is not working so I expect to be going on something else soon, probably the Gab -- . My pain started before I went into the dentist and of course I thought he would fix it. He gave me a cap on a tooth, which I practically insisted on, and then I kept calling and complaining the pain had gotten worse. So, he sent me to a Endodontist who gave me some medication which did not work. I complained and finally she did one root canal, I complained, and she did another. I still thought I needed another but she said I just had jaw stiffness and to relax it. I went back to my dentist and got a tooth guard and then he sent me to another specialty dentist. The specialty dentist thought it was a nerve problem but suggested I have a benign nodule on my tongue removed since at that time the pain seemed located in my tongue. Before I had that done I went to a Ear-Nose-Throat doctor who sent me to a neurologist and that was the end of that journey as I got correctly diagnosed! Thank you for asking. This was the first time I have written all this out. Thankfully I am a fast typer!


Mary said:

Hi Mary Helen....thanks for commenting. When I was having such a problem with the side effects of my meds, I couldn't talk either without some pretty rough pain. Who knows why but that problem has lessened quite a bit too. I'll tell you what, just when I think I've figured out where I stand, things change again. Thank goodness, I've had about two weeks of relative ease but I live in fear those horrible pains will strike again.

You mentioned you had also had dental problems prior to your TN pain. I'm curious as to what happened to you. I asked my neurologist if my bad dental experience could have caused my TN and she said "No!" Personally, I think she's wrong as I've read about several people here who experienced their first episode of TN pain following some kind of dental procedure. Woe be unto my dentist if I ever find out for sure that this hell was visited on me as a result of my bad experience in her office. LOL...she just might be giving my great grandchildren free dental service 20 years from now. I'm just joking but it does seem to me that dentists should be better educated about TN and how to avoid putting their patients in jeopardy. There just seems to be too many coincidences re dental problems precipitating TN pain in the short time I've belonged to this site for there not to be some correlation.

I left a Wall Comment on your page earlier and I look forward to hearing more of your story when you have an opportunity.

~Mary

MaryHelenL said:

Hi Mary, I read your story. I am so sorry you went through all this. It sounds like things have gotten under control now. Your dental problems sound like mine were too. I kept insisting they do something, which they did but only added to the problem as it got worse. I too was astounded by the electric shocks which I had about 3 times. I did not know pain could be so bad but luckily they did not last long, but long enough to about scare me to death!

I am now taking Baclofen 40 mg. total and will probably go up to 60mg slowly. For a while 20 mg was working and then I foolishly cut back because I was doing fairly well. Then it hit me hard so I am now trying to get back to at least feeling better.

I have pain when I eat so I blend everything with a hand blender I have to make it almost liquid. I still have some pain when eating-drinking it. Also, I have sharp pains when I talk which is maddening, but I talk anyway. lol It helps if I talk calmly. Everything is better if I am relaxed.

Anyway, I have just joined this site and have just been diagnosed two months ago so it is all very new to me.